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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
12.42
Human Site:
S721
Identified Species:
21.03
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
S721
S
P
S
S
S
P
S
S
P
A
R
K
N
G
G
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
S721
S
P
S
S
S
P
S
S
P
A
R
K
N
G
G
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
S709
S
P
S
S
S
P
S
S
P
A
R
K
S
G
R
Dog
Lupus familis
XP_544874
2297
257913
S721
L
P
S
P
L
P
R
S
P
G
P
K
K
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
Y721
S
S
V
P
S
S
P
Y
R
K
A
A
T
E
W
Rat
Rattus norvegicus
XP_001055500
2294
257490
H720
S
S
A
P
S
S
P
H
R
K
A
A
A
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
N721
A
F
P
S
G
L
R
N
D
K
G
E
E
E
D
Chicken
Gallus gallus
XP_001232723
2283
257889
K719
S
D
C
N
S
D
N
K
K
E
K
E
E
D
W
Frog
Xenopus laevis
Q642P2
2270
256829
W717
N
K
E
T
E
E
E
W
D
I
E
R
L
L
Q
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
V744
S
E
P
K
E
C
S
V
K
V
Q
L
Q
R
T
Honey Bee
Apis mellifera
XP_395999
2434
273219
K708
V
S
D
R
V
L
T
K
E
R
T
V
Q
N
M
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
T798
I
G
S
R
K
F
C
T
E
Q
Q
R
L
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
K208
F
L
V
M
T
A
N
K
G
R
R
L
G
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
86.6
40
N.A.
13.3
13.3
N.A.
6.6
13.3
0
0
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
40
N.A.
13.3
20
N.A.
26.6
40
20
0
N.A.
20
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
0
0
0
22
15
15
8
8
0
% A
% Cys:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
0
0
15
0
0
0
0
8
8
% D
% Glu:
0
8
8
0
15
8
8
0
15
8
8
15
15
29
0
% E
% Phe:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
8
8
8
0
8
29
15
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
0
22
15
22
8
29
8
0
0
% K
% Leu:
8
8
0
0
8
15
0
0
0
0
0
15
15
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
8
0
0
15
8
0
0
0
0
15
8
0
% N
% Pro:
0
29
15
22
0
29
15
0
29
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
15
0
15
0
8
% Q
% Arg:
0
0
0
15
0
0
15
0
15
15
29
15
0
8
22
% R
% Ser:
50
22
36
29
43
15
29
29
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
8
8
0
8
8
0
0
8
0
8
0
8
% T
% Val:
8
0
15
0
8
0
0
8
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
22
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _